Invirase

Common Name: saquinavir hard gel caps

How does Invirase work?

Saquinavir is used usually in combination with other anti-HIV (antiretroviral) medications to treat the infection caused by the human immunodeficiency virus (HIV), the virus responsible for acquired immune deficiency syndrome (AIDS). Saquinavir belongs to a class of medications called protease inhibitors. Saquinavir blocks the action of protease, an enzyme that is needed by HIV to multiply. This medication does not cure AIDS and does not prevent it from being spread to others. It does slow further growth or reproduction of HIV when used in combination with other medications, and it seems to slow down the destruction of the immune system. This may help to delay the development of problems that are related to AIDS or HIV disease.

How should I use Invirase?

For people 16 years and older, the recommended dose of saquinavir hard gel caps is 600 mg taken every eight hours with food (anytime within two hours after a meal or large snack). Saquinavir hard gel capsules should be swallowed whole with a full glass of water. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. Do not change your dose unless instructed by your doctor. It is very important to take this medication on a regular basis as prescribed. The doses should be spaced as close to every 8 hours as possible. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double-up on doses. Do not stop taking this medication without telling your doctor. If you miss many doses in a row, talk to your doctor about how to resume dosing. It is not know how soon saquinavir takes effect. With most antiretroviral medications, a response can be seen within the first few days, but it may take 12 to 16 weeks to reach the maximum effect. Store saquinavir hard gel caps at room temperature and protect from excessive light and moisture.

What form(s) does Invirase come in?

Each hard gelatin, light brown and green capsule, marked "Roche" and "0245" on opaque shells, contains saquinavir 200 mg. Nonmedicinal ingredients: lactose, magnesium stearate, microcrystalline cellulose, povidone, sodium starch glycolate, and talc; capsule shell: gelatin, indigotine, iron oxide, and titanium dioxide.

What should I NOT take with Invirase?

Saquinavir should not be taken by anyone who: has a significant sensitivity or allergy to any of the ingredients of the medication is taking the following medications: astemizole cisapride ergot derivatives midazolam pimozide terfenadine triazolam rifabutin rifampin

Are there any other precautions or warnings for Invirase?

Diabetes: Saquinavir hard gel caps may worsen existing diabetes or trigger the onset of diabetes. This may require new medications or changes to current diabetes treatment. Foods: Fatty foods and grapefruit juice increase the body's absorption of saquinavir. Hemophilia: People with hemophilia may have an increased risk of bleeding while taking this medication. Closely monitor episodes of bleeding. Impaired liver function: People with impaired liver function should use saquinavir hard gel caps with caution. Breast-feeding: Breast-feeding is not recommended for women who are HIV-positive. Pregnancy: Adequate studies of the use of this medication by pregnant women are not available. Talk to your doctor for guidance. Children: The use of this medication has not been studied for use by children younger than 16 years of age.