Trental

Common Name: pentoxifylline

How does Trental work?

Pentoxifylline is used for the treatment of chronic circulation disorders of the extremities such as intermittent claudication (peripheral arterial disease). It helps to improve blood flow and leg pain associated with poor circulation. It may allow further distances to be walked before leg pain or cramps occurs. Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

How should I use Trental?

The usual recommended adult starting dose of pentoxifylline is 400 mg twice daily after meals. The dose is adjusted by the doctor over time as needed to a maximum of 400 mg three times daily. The tablets must be swallowed whole. It may take up to two months to see the full beneficial effects of the medication. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones given here, do not change the way that you are taking the medication without consulting your doctor. It is very important that this medication be taken regularly and exactly as prescribed by the doctor. Do not stop taking this medication without first talking with your doctor. If you miss a dose, take it as soon as possible and continue on with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue on with your regular dosing schedule. Do not double doses.

What form(s) does Trental come in?

Each pink, oblong, film-coated, sustained-release tablet contains pentoxifylline 400 mg. Nonmedicinal ingredients: FD&C Red No. 3, hydroxyethyl cellulose, hydroxypropyl methylcellulose, magnesium stearate, polyethylene glycol, povidone, talc, and titanium dioxide.

What should I NOT take with Trental?

Pentoxifylline should not be used by anyone who: is having a heart attack has severe coronary artery disease and, in the doctor's judgment, stimulation of the heart could prove harmful has bleeding has previously had intolerance or allergy to pentoxifylline or other xanthines such as caffeine, theophylline, and theobromine or is allergic to any ingredients of the medication has or has recently had a stomach ulcer

Are there any other precautions or warnings for Trental?

Bleeding: The use of pentoxifylline has been associated with bleeding and prolonged clotting time. The risk of bleeding may be increased by combined treatment with blood-thinning medications such as warfarin. Therefore, pentoxifylline should be used with caution with such medications and only when, in the doctor's judgment, the potential benefit outweighs the risk. Blood pressure: People with low blood pressure may be more sensitive to side effects with the use of this medication. Caution should be exercised and doses increased gradually. Medical conditions: Pentoxifylline is not recommended for people with severely reduced kidney or liver function. Pregnancy: There is not adequate experience with the use of this medication by pregnant women. Pentoxifylline is not recommended for women who are or may become pregnant unless the expected benefits outweigh the potential risk. If you are or may be pregnant, talk to your doctor about the benefits and risks of this medication. Breast-feeding: Pentoxifylline is passes into breast milk. If you are breast-feeding, talk to your doctor about whether you should stop taking the medication or stop breast-feeding. Children and adolescents: The use of pentoxifylline by people below the age of 18 years is not recommended, as its safety and effectiveness have not been established for this age group. Seniors: Seniors may be more sensitive to the side effects of this medication.