Avapro

Common Name: irbesartan

How does Avapro work?

Irbesartan belongs to a family of medicines known as angiotensin II receptor blockers. These medicines are used to lower high blood pressure and work by relaxing blood vessels. Angiotensin II is a chemical that the body releases to cause the constriction of blood vessels. Irbesartan blocks the action of angiotensin II, resulting in the relaxation of the blood vessels. This relaxation causes the blood pressure to decrease. The full effects of irbesartan are usually seen within about 4 weeks. It can be used alone or in combination with thiazide diuretics (water pills, e.g., hydrochlorothiazide). Your doctor may choose to use this medication for other conditions not listed here. If you're unsure why you are taking this medication, contact your doctor.

How should I use Avapro?

The usual starting dose of irbesartan is 150 mg daily at approximately the same time each day, with or without food (but taken in the same manner each day). The doctor may decide to increase the dose to 300 mg once a day if the blood pressure has not come down enough. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor. If you miss a dose but remember it within 12 hours, take it as soon as possible and then go back to your regular dose. If it is more than 12 hours later than your usual dose, skip that dose and carry on as usual with your next dose. Never double up on doses. It is important to take this medication regularly and to follow the doctor's instructions regarding monitoring blood pressure to ensure that you receive the maximum benefit from the medication. Irbesartan should be stored at normal room temperature in a dry place (not in the bathroom).

What form(s) does Avapro come in?

Avapro® is available in strengths of 75 mg, 150 mg, and 300 mg. 75 mg: Each white-to-off-white, oval tablet, with a heart shape imprinted on one side and "2771" on the other, contains irbesartan 75 mg. 150 mg: Each white-to-off-white, oval tablet, with a heart shape imprinted on one side and "2772" on the other, contains irbesartan 150 mg. 300 mg: Each white-to-off-white, oval tablet, with a heart shape imprinted on one side and "2773" on the other, contains irbesartan 300 mg. Nonmedicinal ingredients: croscarmellose sodium, lactose, magnesium stearate, microcrystalline cellulose, poloxamer 188, pregelatinized starch, and silicon dioxide.

What should I NOT take with Avapro?

This medication should not be taken by: anyone who is allergic to any of the ingredients of the product pregnant women

Are there any other precautions or warnings for Avapro?

Pregnancy: Irbesartan should not be taken during pregnancy. If you discover you are pregnant while taking this medication, stop taking it and tell your doctor at once. Breast-feeding: Breast-feeding is generally not recommended because of the possibility of serious side effects to the infant. Discuss this with your doctor. Children: The safety and effectiveness of irbesartan for children are unknown. Low blood pressure: Occasionally, a larger-than-expected decrease in blood pressure occurs after taking irbesartan. In some cases, this happens after the first dose. It is more likely to occur if you take diuretics (water pills), have a reduced salt intake, are on dialysis, or are experiencing diarrhea or vomiting. Blood pressure should be monitored more often in these situations. Those with low blood pressure or those just starting to take this medication should move slowly from a reclining to an upright position to reduce the risk of dizziness. Kidney problems: Irbesartan may affect the function of the kidneys, especially in those who already have kidney problems. Make sure to tell your doctor if you have kidney problems so that he or she can closely your kidney function. Liver problems: The ability of the body to break down (eliminate) irbesartan may be affected in people with below normal liver function. Be sure to tell your doctor if you have liver problems. Occupational hazards: Dizziness and lightheadedness may occur, especially if you have been taking a diuretic (water pill). Make sure you know how you react to this medicine before you drive, use machines, or do anything else that would be dangerous if you were dizzy or lightheaded. Medical conditions: Be sure to tell your doctor if you have any of the following conditions, as they may affect your use of this medication: valvular stenosis (narrowing of the heart valves) heart disease recent heart attack or stroke